The Tennessee Titans play AFC South rival Houston Texans two times in 2025. The first matchup is in Week 4 in Houston, and the second will be in Week 11 at home against the Texans.
The Titans split the season series with the Texans in 2024. First, the Titans shocked the Texans, winning 32-27 at NRG Stadium on November 24, 2025. Then, the Texans returned the favor on January 5, 2026, in Week 18, winning 23-14. The Texans are the AFC South favorite, while the Titans are projected to be one of the worst teams in the NFL.
Key Takeaways
The Titans will play the Texans on September 28, 2025, in Week 4, from NRG Stadium.
The Texans are currently favored by six points to win at home, and are -3 on the road.
Titans vs. Texans Odds: Who Is Favored To Win?
The Texans are currently favored to defeat the Titans by six points when the teams face off in Houston in Week 4. This implies that oddsmakers believe the Texans will beat the Titans by at least a touchdown.
Team
Titans
Texans
Spread
+6 (-110)
-6 (-110)
Total
44.5 (-110)
44.5 (-110)
Moneyline
+195
-238
What The Spread Tells Us
The spread indicates that the Texans are the favorites, but it's not an overwhelming line. This is based on the fact that the Titans went into Houston and won last season, showing oddsmakers that they know how to win at NRG Stadium, and have competed with them, going 3-1 in the last four games in Houston, and 3-1 against the spread.
What The Moneyline Tells Us
The moneyline indicates that the Texans are the favorite, being the better team and the current AFC South champion after last season. The oddsmakers have given them the odds in both games against the Titans this season.
How The Titans Win Against the Texans
It's all about moving the chains and running the football. That is what the Titans did last season, when Tony Pollard ran 24 times for 119 yards and one touchdown in the 32-27 win over the Texans. Will Levis was also efficient, going 18 for 24 with 278 yards, two touchdowns, and one interception. Cam Ward will get his chance to start and will also present a threat on the ground. The defense must get off the field, and stop the Texans from producing on offense.
How The Texans Win Against the Titans
The Texans can win against the Titans by running the football well with Joe Mixon and setting up more manageable third downs. Ultimately, CJ Stroud must be the man who makes it happen with quick decisions and good passes to Nico Collins and the rest of his receivers. The defense must stack the box to contain Pollard and force Ward to beat them.
Here you'll find the best odds and lines for Titans vs. Texans found at Tennessee sportsbooks.
History of Titans vs. Texans
The Titans and Texans have a rivalry rooted in their shared ties to Houston. Before they moved to Nashville, the Titans were the Houston Oilers. Yes, the Texans are 4-1 in the last five games against the Titans, but the loss last season and two of the previous close wins have reminded everyone that this is a tight showdown.
The Titans' record vs. the Texans
The Titans lead the all-time, head-to-head series 24-22 over their 46 games against one another. So far, they have not met in the postseason, but that b
All-Time Best Titans vs. Texans Games
There have been numerous great games between the two teams over the past 24 years. We isolated four of the absolute best games to highlight.
1. Titans vs. Texans - December 10, 2006
This was the first time Vince Young returned to Houston since leading the city to a College Football National Championship, and he was glorious, running for a game-winning, 39-yard touchdown in overtime to give the Titans the win.
2. Titans vs. Texans -November 23, 2009
Young engineered a game-winning drive in this game, which set up Rob Bironas to hit the game-winning field goal to seal the game for the Titans, and another win in Houston.
3. Titans vs. Texans -January 9, 2002
The Titans needed a win in this game and got it, clinching the top seed in the AFC with a victory over their divisional rivals. Julio Jones scored his first and only touchdown for the Titans.
4. Texans vs. Titans - October 18, 2020
This was the most explosive game in series history, with Derrick Henry going off for 264 yards and two touchdowns, including the game-winning score in a 42-36 overtime victory.
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How to Watch Titans vs. Texans
The Titans vs. Texans Week 4 game will air on CBS in local markets at noon CT. Out-of-market fans can catch the game on NFL Sunday Ticket, which is exclusively on YouTube TV.
FAQs
The Titans currently lead the all-time, head-to-head series 24-22. Recently, the Texans have had the upper hand, going 4-1 in their past five games against the teams, and the series was split last season.
The Titans will play the Texans in Houston in Week 4 on Sunday, September 28, 2025, with the game scheduled for 1:00 PM Eastern and broadcast on CBS Sports. The Titans will host the Texans in Nashville, Tennessee, in Week 11, with the current TV schedule being subject to change.
The Titans won the first-ever game played against the Texans, beating them 17-10 on November 10, 2002, at the Coliseum in Nashville, Tennessee. The Titans also won 13-3 in their return to Houston on December 29, 2002.
The Texans are currently favored to beat the Titans by six points in their Week 4 contest in Houston and by three points in their Week 11 clash in Nashville. The odds can change depending on how the teams do this season.
You can place a bet by utilizing any of the local affiliate sports betting websites. Some of these websites include FanDuel, DraftKings, bet365, BetMGM, Caesars Sportsbook, and you can bet on the moneyline, the spread, and the over/under.
Wes is an editor and writer for BetTennessee.com. Based out of the Kansas City area, Wes has covered sports professionally since 2015 with a strong emphasis on sports betting and the NFL, though he's also covered pro wrestling, UFC, college sports and more.
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